Background: Large-core biopsies or open biopsies with needle localizat
ion have been the mainstay of treatment for evaluating nonpalpable mam
mographic abnormalities. The newly introduced Advanced Breast Biopsy i
nstrumentation (ABBI) system combines digital stereotactic imaging wit
h a highly developed single-use biopsy device to locate and remove a r
adiographically discovered breast lesion to an accuracy of I mm. Study
Design: We conducted a review of the first 58 cases involving the use
of the ABBI system. This: article evaluates the accuracy of specimen
targeting, the success rate of lesion removal, the operative complicat
ions, the mechanical difficulties, and patient satisfaction with the A
BBI system. Results: The lesion was removed successfully in 47 of the
58 cases. Nine patients were eliminated in initial screening and the p
rocedure could not be completed in two. Although the success rate was
high, 14 of the procedures required conversion to ''open'' ABBI proced
ures for completion of the biopsy. Conclusions: The ABBI system is an
alternative to open biopsy with needle localization or large-core biop
sy for nonpalpable mammographic abnormalities. This technique allows c
omplete removal of the lesion in a onestep procedure. The ABBI system
has certain limitations and mechanical problems, at least currently, a
nd offers an advantage over current diagnostic modalities in a very li
mited number of cases only. (C) 1997 by the American College of Surgeo
ns.