Gch. Yang et Wi. Kuhel, UNCOMMON TUMORS OF THE SALIVARY-GLAND IN FINE-NEEDLE ASPIRATION BIOPSIES - A SURGEONS PERSPECTIVE, Acta cytologica, 41(4), 1997, pp. 1015-1022
OBJECTIVE: To determine the utilization of fine needle aspiration (FNA
) biopsy in guiding the surgeon in the management of patients with par
otid masses and to study the cytohistologic correlations of rare parot
id tumors. STUDY DESIGN: FNA biopsies and parotidectomies performed by
a head-and-neck surgeon over an approximate three-year period were an
alyzed. Cytologic features of rare salivary gland tumors were also stu
died and correlated with their histology. RESULTS: In an acinic cell c
arcinoma in a 15-year-old female whose smears were stained with Diff-Q
uik, novel negative images of crystals were found intracytoplasmically
and extracellularly, corresponding to the crystallized, membrane-boun
d, exocrine, secretory substance ultrastructurally. A truly malignant
mixed tumor from a 73-year-old female showed capsular invasion in the
primary site that later metastasized to tile lung with both epithelial
and mesenchymal components. The firmer cells did not exhibit nuclear
atypia except for fine cytoplasmic vacuoles in the Diff-Quik-stained s
mears. Basal cell adenoma, membranous (dermal analogue) type, from an
87-year-old female had an interesting geographic pattern on smears. CO
NCLUSION: Within three years, a total of 70 FNAs were performed. Of th
ose cases, 46 had surgery. Preoperative FNAs of the salivary gland les
ions were utilized by the surgeon in guiding treatment options for lar
ge, fixed masses as well as masses < 1 cm, in elderly and acquired imm
unodeficiency syndrome patients.