Objective: We describe a 29-year-old man with gliosarcoma in the lateral ve
ntricle. Case: The patient presented with headache and impairment of consci
ousness. Computed tomography and magnetic resonance imaging localized the t
umor to the right lateral ventricle and showed heterogeneous enhancement wi
th administration of contrast agents. The tumor was partially removed via a
transcallosal approach. Histologic examination disclosed gliosarcoma arisi
ng by malignant transformation of an ependymoma. Postoperative course: The
patient died of tumor progression 78 days after admission, despite intensiv
e radiotherapy and chemotherapy.