Depressive disorders are of high clinical and economic relevance in outpati
ent and inpatient care. For the treatment of depression effective measures,
are available. However, these methods often are not used because depressiv
e disorders are underdetected or underestimated in their severity. To impro
ve diagnostic and therapeutic processes in the last years different nationa
l and international organizations developed guidelines for diagnosis and tr
eatment of depressive disorders (e.g. AHCPR, APA, German Association of Psy
chiatrists). These guidelines differ substantially in their goals, content,
size, specifically in their methodological quality. The Association of the
Scientific Medical Societies in Germany (AWMF) and the German Agency for Q
uality in. Medicine (AQUMED) developed a checklist to evaluate the methodol
ogical quality of guidelines, This manual was used to describe and analyze
the most relevant and actual six guidelines for diagnosis: and treatment of
depressive disorders. Recommendations for further improvement and implemen
tation of these guidelines are given.