Background. Fast-track recovery after coronary artery bypass surgery has in
fluenced patient care positively. Predicting patients who fall off track an
d require prolonged (greater than or equal to7 days) hospitalization remain
s uncertain. The Parsonnet risk assessment score is effective in predicting
length of stay, but is limited by inaccurate subdivision of risk categorie
s. We simplified the Parsonnet risk scale to better identify patients eligi
ble for fast-track recovery. Method: The cases of 604 consecutive patients
who underwent isolated coronary artery bypass grafting (CABG) using cardiop
ulmonary bypass (CPB) were reviewed retrospectively. A rapid recovery proto
col emphasizing reduced CPB time, preoperative intra-aortic balloon pump (I
ABP) criteria, and atrial fibrillation prophylaxis was applied to all patie
nts. The five original divisions of the Parsonnet risk scale were reduced t
o three risk categories: Low (0-10; Group A), Intermediate (11-20; Group B)
, High (>20; Group C). Comparisons of progressive risk categories were anal
yzed to identify predictive factors associated with fast-track outcomes. Re
sults: The thirty-day operative mortality for the entire group was 3.6%. Th
ree clinical features were identified that distinguished risk progression-f
emale gender, reoperative CABG, and increased age. Additionally, the presen
ce of diabetes (p<0.05), congestive heart failure (p<0.01), and peripheral
vascular disease (p<0.001) distinguished Groups A and B, while acute myocar
dial infarction (p<0.05) influenced outcomes in Group C. Group A (48%) mean
risk score 5.9 +/-3.2 was compared to Group B (34%) 14.8 +/-2.6, which was
further compared to Group C (18%) 26.4 +/-2.8. The mean length of stay for
Group A (5.3 +/-4.1 days) was notably less than Group B (6.1 +/-4.7 days;
p<0.05); however, both groups responded favorably to fast-track techniques.
Group C did not respond comparably (9.2<plus/minus>9.2 vs 6.1 +/-4.7 days;
p<0.001) and experienced prolonged recovery. The simplified Parsonnet risk
scale did not identify differences in operative mortality and revealed onl
y pneumonia (p<0.05) and atrial fibrillation (p<0.01) to be greater in Grou
p C. As risk increased, significantly less revascularization was performed
(Group A 3.6<plus/minus>1.2 grafts/patient vs Group B 3.3 +/-1.2 [p<0.01];
Group B 3.3<plus/minus>1.2 vs Group C 2.5 +/-1.0 [p<0.001]). Conclusion: A
simplified Parsonnet risk scale (three categories) is an effective tool in
identifying factors limiting fast-track recovery. Low- and intermediate-ris
k patients represent the majority (82%) and respond well to fast-track meth
ods. High-risk patients (18%) are limited by a greater percentage of female
patients, reoperative CABG, and the very elderly, resulting in fast-track
failure. Strategies to improve recovery in high-risk patients may include e
volving off-pump techniques.