Current estimates suggest that between 0.4% and 8.3% of children and adoles
cents are affected by major depression. We report a favorable response to t
reatment with citalopram by a 15-year-old boy with major depression who exh
ibited palpebral twitching during his first 2 weeks of treatment. This may
have been a side effect of citalopram as it remitted with redistribution of
doses.