Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model

Authors
Kutlin, A Flegg, C Stenzel, D Reznik, T Roblin, PM Mathews, S Timms, P Hammerschlag, MR
Citation
A. Kutlin et al., Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model, J CLIN MICR, 39(10), 2001, pp. 3721-3723
Citations number
20
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
39
Issue
10
Year of publication
2001
Pages
3721 - 3723
Database
ISI
SICI code
0095-1137(200110)39:10<3721:USOCPI>2.0.ZU;2-E
Abstract
We have established an in vitro model of long-term continuous Chlamydia pne umoniae infection in HEp-2 cells. Using transmission electron microscopy, w e demonstrated the presence of spontaneous abnormal chlamydial inclusions s imilar in appearance to the persistent chlamydial forms induced in vitro by treatment with cytokines or antibiotics or by nutrient deprivation.