PAPILLARY ADENOCARCINOMA OF THE SIGMOID COLON ASSOCIATED WITH PSAMMOMA BODIES AND HYALINE GLOBULES - REPORT OF A CASE

We report a case of papillary adenocarcinoma of the sigmoid colon with psammoma bodies and intracytoplasmic hyaline globules. The patient wa s a 59-year-old woman. The tumor showed central ulceration with smooth elevated ridges. Histologically, the tumor was composed of numerous l arge irregular tubular structures accompanying infolded papillary grow th. The tumor cells showed cytoplasmic basophilia and prominent nuclea r atypia. Psammomatous-type calcification was scattered in the tumor s troma as well as in the glandular lumina. In addition, intracytoplasmi c hyaline globules of various sizes were seen in the neoplastic cells. We propose the name papillary adenocarcinoma associated with psammoma bodies and hyaline globules for this tumor. Accumulation of further c ases is needed to clarify the clinical significance of this type of tu mor.