Objectives-To study the prevalence of psychiatric comorbidity assessed by t
he use of a structured clinical interview in a large, representative sample
of patients with spasmodic torticollis (ST) and to test the hypothesis tha
t social phobia would be highly prevalent.
Methods-In a consecutive cohort of 116 patients with ST treated with botuli
num toxin overall psychiatric comorbidity was studied prospectively with th
e structured clinical interview (SCID) for DSM-IV axis I disorders. Physica
l disability and psychosocial variables were also assessed with standardise
d self rating questionnaires.
Results-41.3% of the subjects met DSM-IV clinical criteria A-G for current
social phobia as the primary psychiatric diagnosis. This figure rose to 56%
including secondary and tertiary psychiatric diagnosis. There was no corre
lation between severity of disease (Tsui score severity of pain, body image
dissatisfaction score) and psychiatric comorbidity. The only significant p
redictor of psychiatric comorbidity was depressive coping behaviour (logist
ic regression analysis, p<0.01; OR=10.8). Compared with a representative sa
mple of the general adult population, in the patients with SIC the prevalen
ce of clinically relevant social phobia is 10-fold, of mood disorders 2.4-f
old, and of lifetime psychiatric comorbidity 2.6-fold increased.
Conclusions-A particularly high prevalence of social phobia was found in th
e cohort of patients with ST. The finding of a high prevalence of social ph
obia and depressive coping behaviour as the main predictor of psychiatric c
omorbidity may make a subgroup of patients with ST particularly amenable to
specific psychotherapeutic interventions.