Compressive optic neuropathy caused by renal osteodystrophy - Case report

Compressive optic neuropathy with acute or chronic vision loss has been ass ociated with various skull base tumors, aneurysms, Graves disease, trauma, and, less commonly, fibrous dysplasia and osteopetrosis. The authors presen t a case of acute visual deterioration in a 25-year-old woman who had massi ve calvarial hypertrophy with optic canal stenosis secondary to renal osteo dystrophy (uremic leontiasis ossea [ULO]; bighead disease). Significant Vis ual field restoration was achieved with high-dose corticosteroids followed by optic nerve decompression. This is the first case report of cranial neur opathy associated with ULO.