Primary intranasal transmissible venereal tumour in the dog: A retrospective study of six spontaneous cases

The medical records of six dogs with primary intranasal transmissible vener eal turnout (TVT were reviewed. Epistaxis (4/6), serosasigineous nasal disc harge (2/6), oronasal fistulae (2/6), facial swelling (1/6) and submandibul ar lymphadenopathy (3/6) due to reactive hyperplasia (2/3) and metastasis ( 1/3) were the most common complaints and clinical findings. Diagnosis was m ade by rhinoscopy and confirmed by cytology and histopathology in five dogs and by cytology only in one dog. The microscopic appearance of the tumours with both diagnostic techniques was typical of TVT. Four cases were treate d effectively with four to five weekly cycles of vincristine monotherapy th at resulted in complete resolution of TVT masses in approximately 1 month. One case was resistant to this kind of treatment and another one was lost t o follow-up.