Productive infection of primary macrophages with human herpesvirus 7

Authors
Zhang, Y de Bolle, L Aquaro, S van Lommel, A De Clercq, E Schols, D
Citation
Y. Zhang et al., Productive infection of primary macrophages with human herpesvirus 7, J VIROLOGY, 75(21), 2001, pp. 10511-10514
Citations number
13
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF VIROLOGY
ISSN journal
0022538X → ACNP
Volume
75
Issue
21
Year of publication
2001
Pages
10511 - 10514
Database
ISI
SICI code
0022-538X(200111)75:21<10511:PIOPMW>2.0.ZU;2-Y
Abstract
Here we demonstrate replication of human herpesvirus 7 (HHV-7), a T-lymphot ropic virus, in macrophages. Productive replication was lost after 2 weeks, but HHV-7 DNA was detected up to 1 month after infection. Thus, macrophage s become infected by HHV-7 and might play an important role as a viral rese rvoir, as has been demonstrated for human immunodeficiency virus type 1.