Noninvasive cardiopulmonary exercise (CPX) testing has proven useful i
n the assessment of heart and lung disease, including cardiac and vent
ilatory reserves. CPX includes the monitoring of respiratory gas excha
nge, O-2 uptake and CO2 production, together with minute ventilation a
nd its components-tidal volume and respiratory rate-together with surv
eillance of electrocardiography and blood pressure during supervised,
incremental exercise. Exercise responses in anaerobic threshold and/or
maximal O-2 uptake are used to grade functional capacity objectively
and to predict cardiac reserve (exercise cardiac output), which grades
the severity of chronic cardiac or circulatory failure. CPX also serv
es to distinguish primary cardiac from ventilatory-based exertional dy
spnea.