Sera from 20 male patients with a diagnosis suggestive of myocarditis,
perimyocarditis or pericarditis were found significantly more often t
o have specific IBA antibodies to Chlamydia pneumoniae than sera from
healthy blood donors of the same age and from the same time period. A
less pronounced difference in IgG titres was found between patients an
d blood donors, and IgM antibodies were found only in one patient. A s
triking variation over time in the prevalence of specific antibodies t
o C. pneumoniae was seen in consecutive male blood donors over a 5-yea
r observation period. The findings were discussed and it was concluded
that C. pneumoniae may be associated with inflammatory heart disease.