Biologically active 1-arylpiperazines. Synthesis of new N-(4-aryl-1-piperazinyl)alkyl derivatives of quinazolidin-4(3H)-one, 2,3-dihydrophthalazine-1,4-dione and 1,2-dihydropyridazine-3,6-dione as potential serotonin receptor ligands

Authors
Kowalski, P Kowalska, T Mokrosz, MJ Bojarski, AJ Charakchieva-Minol, S
Citation
P. Kowalski et al., Biologically active 1-arylpiperazines. Synthesis of new N-(4-aryl-1-piperazinyl)alkyl derivatives of quinazolidin-4(3H)-one, 2,3-dihydrophthalazine-1,4-dione and 1,2-dihydropyridazine-3,6-dione as potential serotonin receptor ligands, MOLECULES, 6(9), 2001, pp. 784-795
Citations number
30
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
MOLECULES
ISSN journal
14203049 → ACNP
Volume
6
Issue
9
Year of publication
2001
Pages
784 - 795
Database
ISI
SICI code
1420-3049(200109)6:9<784:BA1SON>2.0.ZU;2-V
Abstract
The synthesis of a series of new n-propyl and n-butyl chain containing 1-ar yl-piperazine derivatives of quinazolidin-4(3H)-one (7) 2-phenyl-2,3-dihydr ophthalazine-1,4-dione (8) and 1-phenyl-1,2-dihydropyridazine-3,6-dione (9) as potential serotonin receptor ligands is described.