Islands of linkage disequilibrium

Authors
Goldstein, DB
Citation
Db. Goldstein, Islands of linkage disequilibrium, NAT GENET, 29(2), 2001, pp. 109-111
Citations number
11
Categorie Soggetti
Molecular Biology & Genetics
Journal title
NATURE GENETICS
ISSN journal
10614036 → ACNP
Volume
29
Issue
2
Year of publication
2001
Pages
109 - 111
Database
ISI
SICI code
1061-4036(200110)29:2<109:IOLD>2.0.ZU;2-U
Abstract
A detailed knowledge of patterns of linkage disequilibrium in human populat ions is widely seen as a prerequisite for effective population-based diseas e gene mapping. New data suggest that linkage disequilibrium is highly stru ctured into discrete blocks of sequence separated by hot spots of recombina tion.