A CHIRAL CHROMOGENIC RECEPTOR HAVING AN OPTICAL RESPONDING FUNCTION FOR CHIRAL RECOGNITION

A viable example of a naked eye-detectable chiral recognition using a novel artificial optical receptor is reported, based on a new strategy , the so-called ''dual optical sensory system'', that involves the int roduction of two indophenol-type chromophores into a calix[4]crown rec eptor with a 1,1'-binaphthyl unit as a chiral barrier. The resulting c onjugate, 1a, which has been synthesized from optically pure (S)-1,1'- bi-2-naphthol is red in color (lambda(max): 515.5 nm; epsilon(max): 14 ,500 dm(3) mol(-1) cm(-1)) in EtOH; the addition of the set of phenylg lycinols, for example, allows la to show an enantioselective coloratio n, enabling detection of the chirality by the naked eye. Properties as a colorimetric sensor for chirality are presented.