Late recurrence of a primitive neuro-ectodermal tumor

Late recurrences after therapy are rare in primitive neuro-ectodermal tumor (PNET). Most recurrences occur within the first 2 years after therapy, alt hough a small number of recurrences may occur up to 5 years after therapy. We present a rare case of a recurrence of PNET in a 31-year-old woman 17 ye ars after her initial presentation. The potential biological implications o f this late recurrence as well as responses to subsequent therapy, includin g temozolomide, are discussed. Copyright (C) 2001 S. Karger AG, Basel.