Synthesis of beta- and gamma-carbolines by the palladium-catalyzed iminoannulation of internal alkynes

Authors
Zhang, HM Larock, RC
Citation
Hm. Zhang et Rc. Larock, Synthesis of beta- and gamma-carbolines by the palladium-catalyzed iminoannulation of internal alkynes, ORG LETT, 3(20), 2001, pp. 3083-3086
Citations number
31
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
20
Year of publication
2001
Pages
3083 - 3086
Database
ISI
SICI code
1523-7060(20011004)3:20<3083:SOBAGB>2.0.ZU;2-C
Abstract
[GRAPHICS] A variety of substituted beta- and gamma -carbolines have been prepared in good to excellent yields by the annulation of internal acetylenes by the te rt-butylimines of N-substituted 3-iodoindole-2-carboxaldehydes and 2-haloin dole-3-carboxaldehydes, respectively, in the presence of a palladium cataly st.