A bis(oxazolinyl)pyrrole as a new monoanionic tridentate supporting ligand: Synthesis of a highly active palladium catalyst for Suzuki-type C-C coupling

Authors
Mazet, C Gade, LH
Citation
C. Mazet et Lh. Gade, A bis(oxazolinyl)pyrrole as a new monoanionic tridentate supporting ligand: Synthesis of a highly active palladium catalyst for Suzuki-type C-C coupling, ORGANOMETAL, 20(20), 2001, pp. 4144-4146
Citations number
36
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANOMETALLICS
ISSN journal
02767333 → ACNP
Volume
20
Issue
20
Year of publication
2001
Pages
4144 - 4146
Database
ISI
SICI code
0276-7333(20011001)20:20<4144:ABAANM>2.0.ZU;2-0
Abstract
Reaction of pyrrole-2,5-biscarbonitrile with 2-amino-2-methyl-1-propanol ga ve the bis{2-(4,4'-dimethyl-4,5-dihydrooxazolyl)}pyrrole (dmoxpH) (1), whic h was deprotonated and reacted with [PdCl2(COD] to give [Pd-2(dmoxp)(2)Cl-2 ] (2) and [Pd-3(dmoxp)(2)Cl-4] (3). The former is an active catalyst in the Suzuki cross coupling of phenylboronic acid with activated and nonactivate d aryl bromides at 70 degreesC and catalyst / substrate ratios of 10(-4) to 10(-5).