Persistence of secretory antiamoebic antibodies in patients with past invasive intestinal or hepatic amoebiasis

In the present work, it was demonstrated that in amoebic dysentery and amoe bic liver abscess patients, the secretory response is long-lasting (> 12 mo nths); and 50% of amoebic dysentery patients developed circulating antiamoe bic IgG in comparison with 100% of amoebic liver abscess individuals. A tot al of 83% of these individuals developed high levels of serum anti-Entamoeb a histolytica IgA. However, only 10.4% of the dysentery patients showed thi s anti-E. histolytica antibody isotype in serum. There was no correlation b etween secretory and serum antiamoebic response, suggesting independent ind uctive and effector sites in both compartments.