Six coumarins have been isolated from the fruits and the stem bark of Calop
hyllum dispar (Clusiaceae). The structures of these minor components were e
stablished by means of spectroscopic analysis, including extensive 2D NMR s
tudies. Some of these coumarins exhibited a significant cytotoxic activity
against KB cells. (C) 2001 Elsevier Science Ltd. All rights reserved.