The indolopyridoquinazoline alkaloid, 3-hydoxyrutaecarpine, was isolated fr
om Leptothyrsa sprucei, along with 8-methoxypsoralen, 5-methoxypsoralen, im
peratorin, imperatorin, kaempferol 3-O-alpha -L-rhamnopyranoside, clematine
and cnidioside B. The usefulness of the gradient H-1=N-15 HMBC NMR spectro
scopy in the structure elucidation of 3-hydroxyrutaecarpine is noted. (C) 2
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