Synthesis of 1-(p-tosyl)pyrazolo[1,5-a]-pyrimidines and pyrazolo [1,5-c]-[1,2,4]triazine derivatives

Authors
Abdel-Razik, HH Fadda, AA
Citation
Hh. Abdel-razik et Aa. Fadda, Synthesis of 1-(p-tosyl)pyrazolo[1,5-a]-pyrimidines and pyrazolo [1,5-c]-[1,2,4]triazine derivatives, SYN COMMUN, 31(22), 2001, pp. 3547-3556
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
22
Year of publication
2001
Pages
3547 - 3556
Database
ISI
SICI code
0039-7911(2001)31:22<3547:SO1AP[>2.0.ZU;2-9
Abstract
Several new pyrazolo[1,5-a]pyrimidines were synthesized by condensation of 3-amino-1,5-dihydro-1-(p-tosyl)pyrazole 2 with bifunctional reagents. Diazo tization of 2 and subsequent coupling with beta -naphthol yielded the corre sponding pyrazolo[1,5-c]-as-triazine derivatives. IR and H-1 NMR spectra fo r all of the hitherto prepared compounds are in good agreement with the pro posed structures.