Voltammetric behavior of vitamin B-2 on the gold electrode modified with aself-assembled monolayer of L-cysteine and its application for the determination of vitamin B-2 using linear sweep stripping voltammetry

The voltammetric behavior of Vitamin B-2 (VB2) has been studied at the gold electrode modified with a self-assembled monolayer Of L-Cysteine. The volt ammetric responses are evaluated with respect experimental conditions, such as composition and pH of the supporting electrolyte, concentration of VB2, accumulation potential and accumulation time. On basis of the voltammetric behavior a highly sensitive method is present for the determination of VB2 by using linear sweep stripping volammetry. The method is suitable for the determination of VB2 concentrations between 5.0 x 10(-11) and 5.0 x 10(-6) mol l(-1). And the detection limit can be reached to 2.5 x 10(-11) mol l(- 1). The method is applied to determine the concentration of VB2 in the tabl ets with satisfactory results. (C) 2001 Elsevier Science BN. All rights res erved.