The objective of this study was to determine cow factors that influence con
ception rates after timed artificial insemination (TAI) on a commercial dai
ry farm. In Trial 1, 197 cows were synchronized by an administration of 25
mg of dinoprost between Days 48 and 54 post partum and again 14 days later.
Cows were inseminated 66 and 90 hours after the second treatment. In Trial
2, 196 cows were treated with an Ovsynch protocol consisting of an adminis
tration of 0.02 mg of buserelin between Days 62 and 68 post partum, a treat
ment with 0.75 mg of tiaprost 7 days later and a second treatment with buse
relin 48 h later. Cows were bred 16 to 20 hours after the last treatment. C
ows with abnormal vaginal discharge at the time of insemination were exclud
ed from AI. Lactation number, milk yield, fat and protein content of milk,
signs of endometritis at an examination 14 to 20 days post partum and month
of breeding were included as potential factors influencing conception on T
AI. Conception rates after timed breeding were 32.0% and 30.6% in Trials 1
and 2, respectively. Logistic regression revealed that neither milk product
ion parameters nor endometritis at post partum. examination influenced conc
eption rates in either of the two timed breeding protocols. Only parity sho
wed an effect (P=0.012) in Trial 2. Primiparous cows were more likely to co
nceive after timed breeding than older cows (43.5 vs. 23.1%). An effect of
parity, however, was not observed in Trial 1. It can be concluded that neit
her milk production nor endometritis at an examination 14 to 20 days post p
artum influence conception rates after TAI if cows with abnormal vulval dis
charge at the designated time of Al are excluded from breeding. (C) 2001 by
Elsevier Science Inc.