Is the nucleus in need of translation?

Authors
Citation
T. Pederson, Is the nucleus in need of translation?, TR CELL BIO, 11(10), 2001, pp. 395-397
Citations number
8
Categorie Soggetti
Cell & Developmental Biology
Journal title
TRENDS IN CELL BIOLOGY
ISSN journal
09628924 → ACNP
Volume
11
Issue
10
Year of publication
2001
Pages
395 - 397
Database
ISI
SICI code
0962-8924(200110)11:10<395:ITNINO>2.0.ZU;2-S
Abstract
In prokaryotic cells, protein synthesis commences on nascent messenger RNAs while they are still being synthesized on the DNA template. The eukaryotic nuclear envelope spatially segregates protein synthesis away from the geno me and messenger RNA production-this being thought to be a defining feature of the Eukarya. New results suggest that the eukaryotic 'standard model' m ight be an oversimplification. How good is the evidence for translation in the cell nucleus, and, if sound, where do the new findings take us?