Bile duct leaks and stenosis, although greatly reduced in their incidence,
still play a major role in early and late graft loss. Their pathogenesis is
multifactorial, being related to graft quality, ischemia time, arterial bl
ood flow, and, of course, technical mishaps. The diagnosis and treatment of
biliary complications is nowadays a joint effort among surgeons, intervent
ional radiologists, and gastroenterologists. The correct algorithm in obtai
ning a fast diagnosis and the correct therapeutic approach are necessary to
save the graft, avoid retransplantation or recipient death. Although this
may seem to be a simple and basic concept, it assumes tremendous importance
in liver transplantation in which the differential diagnosis between bilia
ry and arterial complications or graft rejection and malfunctioning is ofte
n a difficult one.