SELECTIVE DEPROTECTION OF TERT-BUTYLDIMETHYLSILYL ETHER WITH LITHIUM BROMIDE AND 18-CROWN-6

Authors
TANDON M BEGLEY TP
Citation
M. Tandon et Tp. Begley, SELECTIVE DEPROTECTION OF TERT-BUTYLDIMETHYLSILYL ETHER WITH LITHIUM BROMIDE AND 18-CROWN-6, Synthetic communications, 27(17), 1997, pp. 2953-2959
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
27
Issue
17
Year of publication
1997
Pages
2953 - 2959
Database
ISI
SICI code
0039-7911(1997)27:17<2953:SDOTEW>2.0.ZU;2-T
Abstract
Lithium bromide, in the presence of a crown ether, has been found to s electively remove primary tert-butyldimethylsilyl ethers under control led conditions. This selectivity has been utilized to synthesize 3'-TB DMS-2'-deoxyuridine in one step from the diprotected compound.