S. Olgen et Ck. Chu, Synthesis and antiviral activity of 2 '-deoxy-2 '-fluoro-L-arabinofuranosyl 1,2,3-triazole derivatives, Z NATURFO B, 56(8), 2001, pp. 804-811
Citations number
21
Categorie Soggetti
Chemistry
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
The title compounds were prepared by building up the triazole ring at the a
nomeric position via the glycosyl azides 5 a,b. The anomeric configurations
of these nucleosides were assigned by using H-1, C-13 and NOESY NMR spectr
oscopy. The synthesized nucleosides were evaluated against HIV-1 and HBV.