Introduction: Leiomyosarcoma of the urinary bladder is a rare cancer in uro
logy with unknown etiology.
Case Reports: We report the medical history, therapy and follow-up of two a
dditional patients with a leiomyosarcoma of the urinary bladder.
Conclusions: Treatment options are discussed taking into account our own ex
perience as well as a review of the literature. If a localized tumor is dia
gnosed early, radical cystectomy is indicated in adults. Adjuvant therapy p
rotocols based on GTNM-staging and grading have been employed with varying
success.