Objective: The purpose of this study was to assess the efficacy of surveill
ance of nosocomial infection in infection control at a service of general s
urgery.
Design: A surveillance study that included 1483 patients with a prospective
identification of nosocomial infection was carried out. Its results were d
iscussed with the staff, and a program on nosocomial infection control was
implemented. One year after the preintervention study, a similar study that
included 1506 patients was done. The main outcome measure was nosocomial i
nfection. Incidence rates, incidence rate ratios, crude and multiple-risk f
actor adjusted for by Poisson regression analysis, and their 95% confidence
interval rates were estimated.
Results: The characteristics of the patients enrolled in both studies were
compared. After the intervention, the trend was to attend patients with mor
e severe conditions: higher frequency of liver failure, chronic obstructive
lung disease, higher proportion of dirty surgical wounds, and higher score
s of both Study on the Efficacy of Nosocomial Infection Control (SENIC) and
National Nosocomial Infections Surveillance indices. There were no signifi
cant differences in emergency surgery, duration of surgery, age, and sex. A
fter the intervention, unnecessary chemoprophylaxis was drastically reduced
, and a significant reduction in preoperative stay was observed. The nosoco
mial incidence rate fell from 18.4 to 14 per 1000 patient-days. This reduct
ion yielded an incidence rate ratio of 0.56 (95% confidence interval, 0.43%
-0.74%) adjusted for several variables (SENIC index, serum creatinine level
, serum albumin level, antihistamine H2 level, surgical wound, body mass in
dex, chemoprophylaxis, and community-acquired infection). Significant reduc
tions in surgical site infection and urinary tract infection were observed,
but the rate of respiratory tract infection remained unchanged.
Conclusions: Surveillance was effective in reducing nosocomial infection.