Given the rise in health care-related expenditures, decision-makers are inc
reasingly relying on both clinical effectiveness and economic efficiency wh
en making health care decisions. The field of infection control is not immu
ne to this rise in cost-consciousness among health care managers. This arti
cle clarifies the role of economic evaluation within infection control for
both the user and producer of economic evaluations in this field. The stren
gths and drawbacks of the several different types of economic analysis-cost
minimization, cost-effectiveness, cost-benefit. and cost utility analysis-
will be discussed. Additionally, the important features of two specific met
hods used for economic evaluation-decision analytic modeling and economic a
nalysis alongside a clinical trial-will be outlined. Finally, the criteria
by which economic analyses should be judged will be provided. As economic e
valuation and health services research continue, to play an increasingly im
portant role in health care, it will be vital for infection control advocat
es to partner with individuals from diverse fields to give decision-makers
the type of information they need to make choices.