Application of liposomes together with thin layer potentiometry for detection of odorant compounds interaction with lipid layer

Herein we present a study on the application of a thin-layer potentiometry for detection of an interaction of odorants with liposome lipid layer. Thre e different kinds of liposomes: neutral (phosphatidylcholine + cholesterol) , negatively charged (with dicetylphosphate) and positively charged (with s terylamine), were applied for study of the influence of charge on the inter action with odorants. The relative marker ion tetrabutylammonium (TBA(+)) r elease from the interior of liposomes upon stimulation by odorants was used as a measure of their interaction with the lipid layer.