A. Nikolova et al., Preparation, physicochemical characterization and pharmacological study ofnovel ruthenium(III) complexes with imidazole and benzimidazole derivatives, ARZNEI-FOR, 51(9), 2001, pp. 758-762
Complex compounds of ruthenium(III) with 1,2-dimethylimidazole (CAS 1739-84
-0), 2-phenylimidazole (CAS 670-96-2) and 2-aminobenzimidazole (CAS 934-32-
7) were prepared and were characterised. by physicochemical methods. Coordi
nation sites were determined. The complexes were tested for cytotoxic activ
ity using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
) dye-reduction assay and the values LD50 were evaluated.