Order-restricted score tests for homogeneity in generalised linear and nonlinear mixed models

Citation
Db. Hall et Jt. Praestgaard, Order-restricted score tests for homogeneity in generalised linear and nonlinear mixed models, BIOMETRIKA, 88(3), 2001, pp. 739-751
Citations number
18
Categorie Soggetti
Biology,Multidisciplinary,Mathematics
Journal title
BIOMETRIKA
ISSN journal
00063444 → ACNP
Volume
88
Issue
3
Year of publication
2001
Pages
739 - 751
Database
ISI
SICI code
0006-3444(200109)88:3<739:OSTFHI>2.0.ZU;2-6
Abstract
Lin (1997), building on work by Solomon & Cox (1992) and Lin & Breslow (199 6), introduced a score test for homogeneity in the generalised linear mixed model. In this paper we propose an improvement to Lin's test that exploits the fact that covariance parameters associated with random effects in the model are constrained so as to form a positive semidefinite covariance matr ix. Therefore, an omnibus score test will have power against alternatives t hat are known never to occur. Our improvement works by concentrating the sc ore test into directions given by the positive semidefiniteness constraint. We apply the same sort of modification to the bias-corrected version of he r score test in the generalised linear mixed model context and, in a nonlin ear mixed model context, to a score test analogous to hers. We show how to obtain the limiting distribution of our proposed test statistic. We also ar gue, via simulations and local alternative power calculations, that the res tricted test has better power than the unrestricted one.