Citation
T. Kimitsuki et al., Membrane current possessing the properties of a mechano-electric transducer current in inner hair cells of guinea-pig cochlea, BRAIN RES, 915(1), 2001, pp. 101-103
Citations number
18
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993
→ ACNP
Volume
915
Issue
1
Year of publication
2001
Pages
101 - 103
Database
ISI
SICI code
0006-8993(20011005)915:1<101:MCPTPO>2.0.ZU;2-2
Abstract
We measured the membrane current possessing the properties of a mechano-ele
ctric transducer current in isolated inner hair cells of guinea-pig cochlea
. In a free-standing hair bundle, depolarization to + 80 mV evoked a stable
outward current attributable to the opening of transducer channels, and re
polarization to -80 mV evoked a transient inward current indicating adaptat
ion. The time constant of adaptation increased as the membrane potential de
polarized. Dihydrostreptomycin diminished both the outward and inward curre
nts. (C) 2001 Elsevier Science BY All rights reserved.