The biologic basis of fatigue

Authors
Citation
Hb. Gutstein, The biologic basis of fatigue, CANCER, 92(6), 2001, pp. 1678-1683
Citations number
25
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
CANCER
ISSN journal
0008543X → ACNP
Volume
92
Issue
6
Year of publication
2001
Supplement
S
Pages
1678 - 1683
Database
ISI
SICI code
0008-543X(20010915)92:6<1678:TBBOF>2.0.ZU;2-F
Abstract
In spite of many remarkable advances in our understanding of the mechanisms of cancer biology, very little attention has been directed toward mechanis ms underlying cancer-induced symptoms. Although fatigue is a widely prevale nt complication of cancer, there is a paucity of both basic and clinical re search in this area. This article details our current knowledge of mechanis ms causing cancer-related fatigue and briefly discusses currently available therapeutic options. A framework for addressing gaps in our knowledge and recommendations for future research directions are proposed. (C) 2001 Ameri can Cancer Society.