Cancer-related fatigue is now the most prevalent symptom of cancer, occurri
ng in 60-90% of patients. Fatigue has been identified by cancer patients as
a factor influencing functionality and quality of life. Our objectives in
developing a fatigue specialty clinic at The University of Texas M. D. Ande
rson Cancer Center were to improve our patients' quality of life by decreas
ing fatigue; educate health care providers, patients, and patients' familie
s about cancer-related fatigue; develop an appropriate clinical and diagnos
tic evaluation for this symptom; correlate objective measures of fatigue wi
th its clinical evaluation; and develop innovative treatment plans for canc
er-related fatigue. This article describes the general clinic design and op
erations and the preliminary analysis of the first 40 patients evaluated in
the fatigue clinic. (C) 2001 American Cancer Society.