3 '-Amino-2 ',4 '-BNA: novel bridged nucleic acids having an N3 '-> P5 ' phosphoramidate linkage

Authors
Obika, S Onoda, M Morita, K Andoh, J Koizumi, M Imanishi, T
Citation
S. Obika et al., 3 '-Amino-2 ',4 '-BNA: novel bridged nucleic acids having an N3 '-> P5 ' phosphoramidate linkage, CHEM COMMUN, (19), 2001, pp. 1992-1993
Citations number
23
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
19
Year of publication
2001
Pages
1992 - 1993
Database
ISI
SICI code
1359-7345(20011007):19<1992:3'''NB>2.0.ZU;2-A
Abstract
Novel oligonucleotide analogues, containing a 3'-amino-2',4'-BNA unit, were successfully synthesized, and they showed superior duplex and triplex form ing ability as well as BNA itself, along with remarkable enzymatic stabilit y.