Imaging posterior polymorphous corneal dystrophy by in vivo confocal microscopy

To identify features of posterior polymorphous dystrophy (PPMD) by in vivo confocal microscopy, the corneas of a female patient with PPMD were examine d using slit-lamp biomicroscopy and slit-scanning in vivo confocal microsco py. Characteristic endothelial vesicular and band lesions were seen clinica lly and easily identified using in vivo confocal microscopy. However, endot helial pleomorphism, an increased density and reflectance of posterior stro mal keratocytes, and prominence of corneal nerves were also delineated. In vivo confocal microscopy enhances clinicopathological diagnosis and follow up of corneal dystrophies with subtle clinical presentations, such as PPMD.