Total ankle arthroplasty is emerging as a viable treatment for patients wit
h symptomatic tibiotalar arthritis who have not responded to nonoperative t
reatment. First generation ankle replacement prostheses had significant com
plications, leading many orthopaedic surgeons to abandon their use. Second
generation designs have attempted to address some of these problems wit inn
ovative new designs. Ankle arthritis differs from other forms of degenerati
ve arthritis in that the majority is posttraumatic in origin, and occurs in
a younger age group. Correction of alignment is complicated by deformity o
f the foot distal to the ankle. Published results of second generation ankl
e replacement systems are limited, and the understanding of them is necessa
rily anecdotal. In the current study, complications of current second gener
ation total ankle arthroplasty are divided into preoperative or patient sel
ection problems, complications related to prosthetic design, intraoperative
, and postoperative complications. Solutions, or the controversies surround
ing those complications that have no obvious solution, will be discussed wh
en appropriate. Total ankle arthroplasty with these second generation prost
heses is gaining increasing popularity. The surgeon contemplating total ank
le arthroplasty should have an understanding of anatomy and lower extremity
biomechanics, and a thorough knowledge of the total ankle system he or she
decided to use.