Hj. Grabe et al., Lifetime-comorbidity of obsessive-compulsive disorder and subclinical obsessive-compulsive disorder in northern Germany, EUR ARCH PS, 251(3), 2001, pp. 130-135
Objective Inspite of the worldwide relevance of obsessive-compulsive disord
er (OCD), there is a substantial lack of data on comorbidity in OCD and sub
clinical OCD in the general population. Methods German versions, of the DSM
-IV adapted Composite International Diagnostic Interview were administered
to a representative sample of 4075 persons aged 18-64 years, living in a no
rthern German region. Results In both genders, high rates of comorbid depre
ssive disorders were found in OCD and subclinical OCD, whereas somatoform p
ain disorder was only associated with OCD. In female subjects,,OCD was addi
tionally associated with social and specific phobias, alcohol, nicotine and
sedative dependence, PTSD and atypical eating, disorder. Conclusion Due to
low comorbidity rates, subclinical OCD seems to represent an independent s
yndrome not restricted to the presence of other axis-1 diagnoses. Comorbidi
ty patterns show a disposition to, anxiety and to depressive disorders in O
CD and subclinical OCD. A broad association with obsessive-compulsive spect
rum disorders could not be confirmed in our general population sample.