The objective of this study was to assess whether smoking habits can explai
n the decline in left-handedness prevalence with age. Subjects participatin
g in a population-based survey (n=3,071) in Geneva, Switzerland, completed
a questionnaire on innate hand preference, current hand preference for writ
ing and smoking habits. The prevalence of innate left-handedness in the Gen
eva population was 9.4% in men and 7.4% in women. There was no association
between smoking and left-handed ness. It is concluded that smoking is not a
ssociated with hand preference and is an unlikely cause of overmortality in
left-handed subjects.