Despite the limitations of US in providing a complete evaluation of renal t
umors before treatment planning, initial screening, characterization of ren
al masses and staging of RCCs can benefit from some recent advances of the
technique. One of the most relevant clinical benefits of US is the increase
d early detection of RCCs. Recent technical improvement of gray-scale imagi
ng has increased US performance in the detection of small renal tumors. Com
bined gray-scale and color Doppler US findings may strongly suggest the his
topathologic nature of a renal tumor with respect to the size, the US atten
uation characteristics, and the vascular distribution of the lesion. Ultras
ound contributes additional diagnostic information for differential diagnos
is of some renal masses that remain equivocal at CT, including: atypical cy
stic lesions; solid renal tumors with poor vascularity; and angiomyolipomas
with minimal fat component. Ultrasound also may provide additional diagnos
tic information over CT in selected cases of RCCs with venous invasion. In
addition to some diagnostic and therapeutic procedures that can benefit fro
m US guidance, intraoperative US remains the only available tool that enabl
es to ensure renal-parenchymal-sparing surgery.