FLUCONAZOLE FOR TREATMENT OF FUNGAL-INFECTIONS OF THE URINARY-TRACT IN CHILDREN

Two children with fungal urinary tract infections (UTI) were treated w ith fluconazole. One had bilateral megaureters, an almost non-function ing right kidney, and a moderately functioning left kidney because of severe vesicoureteric reflux. He underwent a ureteric reimplantation p rocedure but developed a fungal UTI postoperatively. The other child h ad bilateral refluxing megaureters, one of which appeared to open ecto pically into the urethra. He acquired a fungal infection during intens ive and prolonged antibiotic therapy for a bacterial UTI and septicaem ia in the neonatal period. Both fungal infections were cured successfu lly. We recommend fluconazole as a safe and effective antifungal agent that may be used as a drug of choice for this difficult problem.