Hypopotassemic paralysis: A rare presentation of proximal renal tabular acidosis

Neurologic manifestations can accompany systemic diseases, and primary dise ase can be identified with a careful history, physical examination, and lab oratory investigations. A 14-year-old girl with paraplegia and absence of d eep tendon reflexes in the lower extremities after 2 days of vomiting and d iarrhea was referred to our pediatric neurology department with a diagnosis of Guillain-Barre syndrome. Short stature, dehydration, motor and mental r etardation, bilateral cataracts, glaucoma, and band keratopathy were detect ed on physical examination. Hypopotassemia and severe metabolic acidosis we re found on biochemical examination. Her paraplegia improved after appropri ate fluid and electrolyte replacement, but metabolic acidosis persisted aft er cessation of intravenous therapy, and isolated proximal renal tubular ac idosis was detected. Because she had isolated proximal renal tubular acidos is and other abnormalities, she was diagnosed with Doncker-wolcke-Winsnes s yndrome.