Immunomodulatory activity of Punica granatum in rabbits - a preliminary study

Authors
Ross, RG Selvasubramanian, S Jayasundar, S
Citation
Rg. Ross et al., Immunomodulatory activity of Punica granatum in rabbits - a preliminary study, J ETHNOPHAR, 78(1), 2001, pp. 85-87
Citations number
9
Categorie Soggetti
Pharmacology & Toxicology
Journal title
JOURNAL OF ETHNOPHARMACOLOGY
ISSN journal
03788741 → ACNP
Volume
78
Issue
1
Year of publication
2001
Pages
85 - 87
Database
ISI
SICI code
0378-8741(200111)78:1<85:IAOPGI>2.0.ZU;2-0
Abstract
Punica granatum L. (Punicaceae) fruit rind powder (PGFRP) at the dose of 10 0 mg/kg orally as aqueous suspension was found to stimulate the cell-mediat ed and humoral components of the immune system in rabbits. PGFRP elicited a n increase in antibody titer to typhoid-H antigen. It also enhanced the inh ibition of leucocyte migration in Leucocyte Migration Inhibition test and i nduration of skin in delayed hypersensitivity test with Purified Protein De rivative (PPD) confirming its stimulatory effect on cell-mediated immune re sponse. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.