Purpose: To expand the understanding of what constitutes evidence for theor
y-guided, evidence-based nursing practice from a narrow focus on empirics t
o a more comprehensive focus on diverse patterns of knowing.
Organizing construct. Carper's four fundamental patterns of knowing in nurs
ing-empirical, ethical, personal, and aesthetic-are required for nursing pr
actice. A different mode of inquiry is required to develop knowledge about
and evidence for each pattern.
Conclusions: Theory, inquiry, and evidence are inextricably linked. Each pa
ttern of knowing can be considered a type of theory, and the modes of inqui
ry appropriate to the generation and testing of each type of theory provide
diverse sources of data for evidence-based nursing practice. Different kin
ds of nursing theories provide different lenses for critiquing and interpre
ting the different kinds of evidence essential for theory-guided, evidence-
based holistic nursing practice.