The aim of this study was to investigate the influence of substrate charact
eristics such as chemical composition and surface morphology of dental cera
mics to support cell attachment and proliferation. Thus, body (B) and shoul
der (S) porcelain differing on their surface morphology and composition wer
e treated with oxides CaO or CaO and P2O5 and four modified ceramics BCa, B
CaP, SCa, SCaP were constructed, respectively. The modified ceramics differ
from their controls concerning their surface morphology as evaluated by Sc
anning Electron Microscope (SEM), and their surface chemical composition (N
a, KP and Ca) as evaluated by Energy Dispersing Spectroscopy (EDS). All mod
ified ceramics support better than the control ceramics the cell proliferat
ion over 72 h incubation period. Furthermore, higher rates of cell prolifer
ation was detected in shoulder modified ceramics (SCa and SCaP) than in all
other cases.